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MitoBloCK-12
- 英文名称:MitoBloCK-12
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10394
- cas:522-51-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10394 |
用途 | 科研检测 |
英文名称 | MitoBloCK-12 |
包装规格 | 1MG |
CAS编号 | 522-51-0 |
别名 | MitoBloCK-12 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C30H40Cl2N4
分子量:527.58
溶剂:DMSO (1 mg/ml) Water (1 mg/ml)
性状:Beige solid
存储:RT
Activity (short version):Mitochondrial import inhibitor
Function / Pharmacology:Attenuates mitochondrial protein import (4-10 uM). Discovered in a screen of FDA-approved drugs. Blocks translocation of a mutant form of alanine: glyoxylate aminotransferase (AGT) to the mitochondria and restores AGT trafficking to peroxisomes.1 Also reduces oxalate accumulation and thus has potential to treat patients with primary hyperoxaluria 1 who possess mutations in AGT.1 Also displays antimicrobial activity2, inhibits apamin-sensitive K+ channels3 and induces apoptosis by inhibiting XIAP4.
分子式:C30H40Cl2N4
分子量:527.58
溶剂:DMSO (1 mg/ml) Water (1 mg/ml)
性状:Beige solid
存储:RT
Activity (short version):Mitochondrial import inhibitor
Function / Pharmacology:Attenuates mitochondrial protein import (4-10 uM). Discovered in a screen of FDA-approved drugs. Blocks translocation of a mutant form of alanine: glyoxylate aminotransferase (AGT) to the mitochondria and restores AGT trafficking to peroxisomes.1 Also reduces oxalate accumulation and thus has potential to treat patients with primary hyperoxaluria 1 who possess mutations in AGT.1 Also displays antimicrobial activity2, inhibits apamin-sensitive K+ channels3 and induces apoptosis by inhibiting XIAP4.