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NSC33994
- 英文名称：NSC33994
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10398
- cas：82058-16-0
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10398 |
| 用途 | 科研检测 |
| 英文名称 | NSC33994 |
| 包装规格 | 1MG |
| CAS编号 | 82058-16-0 |
| 别名 | NSC33994 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C28H42N2O2
分子量:436.65
溶剂:DMSO (2 mg/ml) Ethanol (4 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):JAK2 inhibitor
Function / Pharmacology:A remarkably potent and selective JAK2 inhibitor (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM1. Suppresses JAK2-V617F-mediated human pathological cell growth in vitro and in vivo2 and is concomitant with the disruption of intracellular vimentin filaments3. Reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo4.
分子式:C28H42N2O2
分子量:436.65
溶剂:DMSO (2 mg/ml) Ethanol (4 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):JAK2 inhibitor
Function / Pharmacology:A remarkably potent and selective JAK2 inhibitor (IC50 = 60 nM). Displays no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM1. Suppresses JAK2-V617F-mediated human pathological cell growth in vitro and in vivo2 and is concomitant with the disruption of intracellular vimentin filaments3. Reduces the tumorigenic potential of T98G glioblastoma cells in vitro and in vivo4.
