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GW-501516
- 英文名称:GW-501516
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10405
- cas:317318-70-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10405 |
用途 | 科研检测 |
英文名称 | GW-501516 |
包装规格 | 1MG |
CAS编号 | 317318-70-0 |
别名 | GW-501516 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C21H18F3NO3S2
分子量:453.50
溶剂:DMSO (40 mg/ml) Ethanol (20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):PPARδ agonist
Function / Pharmacology:Potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance.2 Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation.3 Upregulates human Sirt1 via Sp1 activation.4 Along with exercise, GW-501516 synergistically increases running endurance.5
分子式:C21H18F3NO3S2
分子量:453.50
溶剂:DMSO (40 mg/ml) Ethanol (20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):PPARδ agonist
Function / Pharmacology:Potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance.2 Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation.3 Upregulates human Sirt1 via Sp1 activation.4 Along with exercise, GW-501516 synergistically increases running endurance.5