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BTB-1
- 英文名称:BTB-1
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10406
- cas:86030-08-2
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10406 |
用途 | 科研检测 |
英文名称 | BTB-1 |
包装规格 | 1MG |
CAS编号 | 86030-08-2 |
别名 | BTB-1 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C12H8ClNO4S
分子量:297.71
溶剂:DMSO (30 mg/ml)
性状:White or off-white solid
存储:RT
Activity (short version):Mitotic kinesin Kif18A inhibitor
Function / Pharmacology:A selective, ATP-competitive and reversible inhibitor of mitotic kinesin Kif18A, IC50=1.7 ?M.1,2 Binds to an allosteric site near Kif18A loop 5 preventing a range of conformational changes thereby blocking motor function.3 Inhibits the differentiation of mouse bone marrow cells to dendritic cells.4 Suppresses the replication of influenza A virus, inhibiting activation of AKT, p38 MAPK, SAPK and RanBP3 leading to the prevention of nuclear export of viral ribonucleoprotein complexes. Greatly improves the viability of IAV-infected mice.5
分子式:C12H8ClNO4S
分子量:297.71
溶剂:DMSO (30 mg/ml)
性状:White or off-white solid
存储:RT
Activity (short version):Mitotic kinesin Kif18A inhibitor
Function / Pharmacology:A selective, ATP-competitive and reversible inhibitor of mitotic kinesin Kif18A, IC50=1.7 ?M.1,2 Binds to an allosteric site near Kif18A loop 5 preventing a range of conformational changes thereby blocking motor function.3 Inhibits the differentiation of mouse bone marrow cells to dendritic cells.4 Suppresses the replication of influenza A virus, inhibiting activation of AKT, p38 MAPK, SAPK and RanBP3 leading to the prevention of nuclear export of viral ribonucleoprotein complexes. Greatly improves the viability of IAV-infected mice.5