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UCF-101
- 英文名称:UCF-101
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10407
- cas:313649-08-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10407 |
用途 | 科研检测 |
英文名称 | UCF-101 |
包装规格 | 1MG |
CAS编号 | 313649-08-0 |
别名 | UCF-101 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC
分子式:C27H17N3O5S
分子量:495.51
溶剂:DMSO (30 mg/ml with warming) DMF (25 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):Omi/HtrA2 protease inhibitor
Function / Pharmacology:UCF-101 is a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 μM for His-Omi134-458). Shows very little activity against various other serine proteases tested (IC50 ≥ 200 μM).1 Mitigates streptozotocin-induced cardiomyocyte dysfunction.2 Protects against cerebral oxidative injury and cognitive impairment in a rat model.3 Cell permeable.
分子式:C27H17N3O5S
分子量:495.51
溶剂:DMSO (30 mg/ml with warming) DMF (25 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):Omi/HtrA2 protease inhibitor
Function / Pharmacology:UCF-101 is a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 μM for His-Omi134-458). Shows very little activity against various other serine proteases tested (IC50 ≥ 200 μM).1 Mitigates streptozotocin-induced cardiomyocyte dysfunction.2 Protects against cerebral oxidative injury and cognitive impairment in a rat model.3 Cell permeable.