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UCF-101
- 英文名称：UCF-101
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10407
- cas：313649-08-0
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10407 |
| 用途 | 科研检测 |
| 英文名称 | UCF-101 |
| 包装规格 | 1MG |
| CAS编号 | 313649-08-0 |
| 别名 | UCF-101 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC
分子式:C27H17N3O5S
分子量:495.51
溶剂:DMSO (30 mg/ml with warming) DMF (25 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):Omi/HtrA2 protease inhibitor
Function / Pharmacology:UCF-101 is a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 μM for His-Omi134-458). Shows very little activity against various other serine proteases tested (IC50 ≥ 200 μM).1 Mitigates streptozotocin-induced cardiomyocyte dysfunction.2 Protects against cerebral oxidative injury and cognitive impairment in a rat model.3 Cell permeable.
分子式:C27H17N3O5S
分子量:495.51
溶剂:DMSO (30 mg/ml with warming) DMF (25 mg/ml)
性状:Orange solid
存储:-20°C
Activity (short version):Omi/HtrA2 protease inhibitor
Function / Pharmacology:UCF-101 is a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 μM for His-Omi134-458). Shows very little activity against various other serine proteases tested (IC50 ≥ 200 μM).1 Mitigates streptozotocin-induced cardiomyocyte dysfunction.2 Protects against cerebral oxidative injury and cognitive impairment in a rat model.3 Cell permeable.
