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ML241
- 英文名称:ML241
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10410
- cas:1346528-06-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10410 |
用途 | 科研检测 |
英文名称 | ML241 |
包装规格 | 1MG |
CAS编号 | 1346528-06-0 |
别名 | ML241 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C23H24N4O
分子量:372.46
溶剂:DMSO (50 mg/ml) Ethanol (14 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):p97 AAA ATPase inhibitor
Function / Pharmacology:Potent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line1. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway.1 ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.2,3
分子式:C23H24N4O
分子量:372.46
溶剂:DMSO (50 mg/ml) Ethanol (14 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):p97 AAA ATPase inhibitor
Function / Pharmacology:Potent and selective p97 AAA ATPase inhibitor, IC50=100 nM. Inhibits degradation of a p97-dependent but not p97-independent proteasome substrate in a dual-reporter cell line1. It impairs the endoplasmic reticulum-associated degradation (ERAD) pathway.1 ML241 and related inhibitors (DBeQ for example) have differential responses to p97 mutants as well as the presence of cofactors suggesting the possibility of context-dependent p97 inhibitors.2,3