菜单 Close 公司首页 公司介绍 公司动态 证书荣誉 联系方式 在线留言
您当前的位置: 网站首页 > 产品展厅 >药物类 >UNC-2170 HCl
UNC-2170 HCl
  • 英文名称:UNC-2170 HCl
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B10412
  • cas:1648707-58-7
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-16
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B10412
用途 科研检测
英文名称 UNC-2170 HCl
包装规格 1MG
CAS编号 1648707-58-7
别名 UNC-2170 HCl
纯度 98+%
分子式
是否进口
纯度:98% by TLC,;NMR (Conforms)
分子式:C14H21BrN2O ? HCl
分子量:349.69
溶剂:DMSO (40 mg/ml) Water (50 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Methyl-lysine binding protein inhibitor
Function / Pharmacology:The DNA damage response protein 53BP1 utilizes its tandem tudor domain to recognize dimethylated lysine 20 on histone (H4K20me2), a modification associated with double-strand DNA breaks. UNC-2170, identified by screening, was found to be a μM ligand for 53BP1 which also demonstrated at least 17-fold selectivity for 53BP1 over other methyl-lysine binding proteins. The compound functions as a 53BP1 antagonist in cell lysates and suppresses class switch recombination in whole cells, a process requiring a functioning 53BP1 tudor domain.1
联系方式
手机:15317051735
Q Q:
二维码扫描访问