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CaCCinh-A01
- 英文名称：CaCCinh-A01
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10442
- cas：407587-33-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10442 |
| 用途 | 科研检测 |
| 英文名称 | CaCCinh-A01 |
| 包装规格 | 1MG |
| CAS编号 | 407587-33-1 |
| 别名 | CaCCinh-A01 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>98% by TLC,;NMR (Conforms)
分子式:C18H21NO4S
分子量:347.43
溶剂:DMSO (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):TMEM16A channel blocker
Function / Pharmacology:CaCCInh-A01 is a potent inhibitor of TMEM16A (IC50 = 2.1 mM), a calcium-activated chloride channel1. Blockade of TMEM16A with CaCCInh-A01 protects against renal fibrosis2, reduces blood brain barrier permeability, attenuates brain infarct size and neurological deficits after ischemic stroke3, and induces apoptosis and cell cycle arrest in various epithelium-originated cancer cells4.
分子式:C18H21NO4S
分子量:347.43
溶剂:DMSO (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):TMEM16A channel blocker
Function / Pharmacology:CaCCInh-A01 is a potent inhibitor of TMEM16A (IC50 = 2.1 mM), a calcium-activated chloride channel1. Blockade of TMEM16A with CaCCInh-A01 protects against renal fibrosis2, reduces blood brain barrier permeability, attenuates brain infarct size and neurological deficits after ischemic stroke3, and induces apoptosis and cell cycle arrest in various epithelium-originated cancer cells4.
