纯度:99% by TLC,;NMR (Conforms)
分子式:C27H43NO3
分子量:429.64
溶剂:DMSO (35 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Endogenous uncoupler of mitochondrial respiration
Function / Pharmacology:An endogenous lipoamino acid produced via the action of a secreted enzyme PM20D1 produced by adipocytes. N-Oleoylphenylalanine binds directly to mitochondria and functions as an endogenous uncoupler of UCP1-independent respiration and is the most potent in the group of structurally different lipoamino acids evaluated. Mice treated with an analog, C18-1-Leu, were found to have improved glucose homeostasis and increased energy expenditure.1