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Itraconazole
- 英文名称：Itraconazole
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10472
- cas：84625-61-6
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10472 |
| 用途 | 科研检测 |
| 英文名称 | Itraconazole |
| 包装规格 | 1MG |
| CAS编号 | 84625-61-6 |
| 别名 | Itraconazole |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C35H36Cl2N8O4
分子量:705.63
溶剂:DMSO (1.5 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Autophagy inducer / inhibits glioblastoma growth
Function / Pharmacology:Itraconazole inhibits the conversion of lanosterol to ergosterol via inhibition of the 14-α demethylase, a cytochrome P-450 enzyme1. Clinically useful antifungal agent. It inhibits the proliferation of glioblastoma cells in vitro and in vivo by inducing autophagic progression via inhibiting the trafficking of cholesterol from late endosomes and lysosomes to the plasma membrane2. Inhibits the hedgehog pathway by binding to Smoothened (SMO) via a mechanism distinct from that of cyclopamine3. Inhibits angiogenesis via inhibiting the binding of VEGF to VEGFR24.
分子式:C35H36Cl2N8O4
分子量:705.63
溶剂:DMSO (1.5 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):Autophagy inducer / inhibits glioblastoma growth
Function / Pharmacology:Itraconazole inhibits the conversion of lanosterol to ergosterol via inhibition of the 14-α demethylase, a cytochrome P-450 enzyme1. Clinically useful antifungal agent. It inhibits the proliferation of glioblastoma cells in vitro and in vivo by inducing autophagic progression via inhibiting the trafficking of cholesterol from late endosomes and lysosomes to the plasma membrane2. Inhibits the hedgehog pathway by binding to Smoothened (SMO) via a mechanism distinct from that of cyclopamine3. Inhibits angiogenesis via inhibiting the binding of VEGF to VEGFR24.
