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Cerulenin
- 英文名称:Cerulenin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10489
- cas:17397-89-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10489 |
用途 | 科研检测 |
英文名称 | Cerulenin |
包装规格 | 1MG |
CAS编号 | 17397-89-6 |
别名 | Cerulenin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C12H17NO3
分子量:223.27
溶剂:DMSO (10 mg/ml) Ethanol (10 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Fatty Acid Synthase inhibitor
Function / Pharmacology:Fatty acid synthase (FAS) inhibitor. Binds to β-keto-acyl-ACP synthase (KAS; IC50=1.5 μM), thus inhibiting protein acylation at concentrations of 45-134 μM1. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream of, both leptin and melanocortin receptors2. Reduces nutrient-induced insulin release from normal rat islets3. Induces apoptosis in human melanoma A-375 cells4.
分子式:C12H17NO3
分子量:223.27
溶剂:DMSO (10 mg/ml) Ethanol (10 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Fatty Acid Synthase inhibitor
Function / Pharmacology:Fatty acid synthase (FAS) inhibitor. Binds to β-keto-acyl-ACP synthase (KAS; IC50=1.5 μM), thus inhibiting protein acylation at concentrations of 45-134 μM1. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream of, both leptin and melanocortin receptors2. Reduces nutrient-induced insulin release from normal rat islets3. Induces apoptosis in human melanoma A-375 cells4.