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Ionomycin
- 英文名称:Ionomycin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10499
- cas:56092-81-0
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10499 |
用途 | 科研检测 |
英文名称 | Ionomycin |
包装规格 | 1MG |
CAS编号 | 56092-81-0 |
别名 | Ionomycin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C41H72O9
分子量:709.01
溶剂:DMSO (10 mg/ml) Ethanol (10 mg/ml)
性状:Yellow oil or waxy solid
存储:-20°C
Activity (short version):Calcium ionophore
Function / Pharmacology:Highly selective nonfluorescent calcium (Ca2+) ionophore.1 Induces a rapid rise in cytosolic Ca2+ in human neutrophils which is due to both release from cytosolic Ca2+ stores as well as Ca2+ influx.2 It activates (2 μM) and primes (20-200 nM) neutrophil NADPH oxidase2. Down regulates beta-catenin/Tcf signaling in a colon cancer cell line via suppressing the binding of Tcf to its specific DNA-binding site.3 In rat hepatoma cells, sub-lethal ionomycin activates the stress response by activating SAPK/JNK and HSF/HSE interaction leading to upregulation of HSP70 biosynthesis.4
分子式:C41H72O9
分子量:709.01
溶剂:DMSO (10 mg/ml) Ethanol (10 mg/ml)
性状:Yellow oil or waxy solid
存储:-20°C
Activity (short version):Calcium ionophore
Function / Pharmacology:Highly selective nonfluorescent calcium (Ca2+) ionophore.1 Induces a rapid rise in cytosolic Ca2+ in human neutrophils which is due to both release from cytosolic Ca2+ stores as well as Ca2+ influx.2 It activates (2 μM) and primes (20-200 nM) neutrophil NADPH oxidase2. Down regulates beta-catenin/Tcf signaling in a colon cancer cell line via suppressing the binding of Tcf to its specific DNA-binding site.3 In rat hepatoma cells, sub-lethal ionomycin activates the stress response by activating SAPK/JNK and HSF/HSE interaction leading to upregulation of HSP70 biosynthesis.4