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Myriocin (ISP-1)
- 英文名称:Myriocin (ISP-1)
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10508
- cas:35891-70-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10508 |
用途 | 科研检测 |
英文名称 | Myriocin (ISP-1) |
包装规格 | 1MG |
CAS编号 | 35891-70-4 |
别名 | Myriocin (ISP-1) |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98%
分子式:C21H39NO6
分子量:401.54
溶剂:DMSO (20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Blocks sphingolipid biosynthesis
Function / Pharmacology:Myriocin is a fungal metabolite with potent immunosuppressant activity.1 It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide.2 It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression.3
分子式:C21H39NO6
分子量:401.54
溶剂:DMSO (20 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Blocks sphingolipid biosynthesis
Function / Pharmacology:Myriocin is a fungal metabolite with potent immunosuppressant activity.1 It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide.2 It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression.3