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Thiolutin
- 英文名称:Thiolutin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10523
- cas:87-11-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10523 |
用途 | 科研检测 |
英文名称 | Thiolutin |
包装规格 | 1MG |
CAS编号 | 87-11-6 |
别名 | Thiolutin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by HPLC;NMR (Conforms)
分子式:C8H8N2O2S2
分子量:228.29
溶剂:DMSO (15 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):DUB PSMD14 inhibitor
Function / Pharmacology:Inhibits the deubiquitinating (DUB) activity of PSMD14 exhibiting potent antitumor activity in neck squamous cell carcinoma in vitro and in vivo1. Inhibits endothelial cell adhesion by perturbing HSP27 interactions with components of the actin and intermediate filament cytoskeleton2. Potently inhibits developmental angiogenesis in zebrafish2. Inhibits adhesion of endothelial cells to vitronectin (IC50=0.83 ?M) inhibiting tumor cell-induced angiogenesis in vivo3. Cell permeable. Active in vivo.
分子式:C8H8N2O2S2
分子量:228.29
溶剂:DMSO (15 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):DUB PSMD14 inhibitor
Function / Pharmacology:Inhibits the deubiquitinating (DUB) activity of PSMD14 exhibiting potent antitumor activity in neck squamous cell carcinoma in vitro and in vivo1. Inhibits endothelial cell adhesion by perturbing HSP27 interactions with components of the actin and intermediate filament cytoskeleton2. Potently inhibits developmental angiogenesis in zebrafish2. Inhibits adhesion of endothelial cells to vitronectin (IC50=0.83 ?M) inhibiting tumor cell-induced angiogenesis in vivo3. Cell permeable. Active in vivo.