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Axitinib
- 英文名称：Axitinib
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10532
- cas：319460-85-0
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10532 |
| 用途 | 科研检测 |
| 英文名称 | Axitinib |
| 包装规格 | 1MG |
| CAS编号 | 319460-85-0 |
| 别名 | Axitinib |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:99% by HPLC,;NMR (Conforms)
分子式:C22H18N4OS
分子量:386.47
溶剂:DMSO (30 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):VEGFR kinase inhibitor
Function / Pharmacology:Potent inhibitor of VEGFR-2, -3, and -1, IC50 = 0.2, 0.1-0.3, and 1.2 nM respectively1 displaying minimal activity against a panel of ~100 protein kinases. Inhibits angiogenesis and vascular permeability.2 Also inhibits BCR-ABL1 (T315I) with high potency, Ki = 149 pM for autophosphorylated ABL1 (T315I).3 Inhibits proliferation of Ba/F3 cells expressing BCR-ABL1 (T315I). Clinically useful anticancer agent.4
分子式:C22H18N4OS
分子量:386.47
溶剂:DMSO (30 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):VEGFR kinase inhibitor
Function / Pharmacology:Potent inhibitor of VEGFR-2, -3, and -1, IC50 = 0.2, 0.1-0.3, and 1.2 nM respectively1 displaying minimal activity against a panel of ~100 protein kinases. Inhibits angiogenesis and vascular permeability.2 Also inhibits BCR-ABL1 (T315I) with high potency, Ki = 149 pM for autophosphorylated ABL1 (T315I).3 Inhibits proliferation of Ba/F3 cells expressing BCR-ABL1 (T315I). Clinically useful anticancer agent.4
