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Dovitinib
- 英文名称:Dovitinib
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10541
- cas:405169-16-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10541 |
用途 | 科研检测 |
英文名称 | Dovitinib |
包装规格 | 1MG |
CAS编号 | 405169-16-6 |
别名 | Dovitinib |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:99% by TLC, 99% by HPLC
分子式:C21H21FN6O
分子量:392.43
溶剂:DMSO (30 mg/ml)
性状:Yellow-green solid
存储:-20°C
Activity (short version):Kinase inhibitor
Function / Pharmacology:Potent kinase inhibitor. Inhibits FLT3 (IC50 = 1 nM), c-KIT (IC50 = 2 nM), FGFR (IC50 = 8 nM), VEGFR1/2/3 (IC50 = 10 nM), PDGFRβ (IC50 = 27 nM), and CSF-1R (IC50 = 36 nM).1 Active in cell culture and in whole animals. Selectively blocks the growth B9 cells transformed by wild type, or activated mutant FGFR3. Induces apoptosis, or sensitizes cells to induction of apoptosis by other means in a variety of cancer cell lines.
分子式:C21H21FN6O
分子量:392.43
溶剂:DMSO (30 mg/ml)
性状:Yellow-green solid
存储:-20°C
Activity (short version):Kinase inhibitor
Function / Pharmacology:Potent kinase inhibitor. Inhibits FLT3 (IC50 = 1 nM), c-KIT (IC50 = 2 nM), FGFR (IC50 = 8 nM), VEGFR1/2/3 (IC50 = 10 nM), PDGFRβ (IC50 = 27 nM), and CSF-1R (IC50 = 36 nM).1 Active in cell culture and in whole animals. Selectively blocks the growth B9 cells transformed by wild type, or activated mutant FGFR3. Induces apoptosis, or sensitizes cells to induction of apoptosis by other means in a variety of cancer cell lines.