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MS-275
- 英文名称：MS-275
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10543
- cas：209783-80-2
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-10-30
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10543 |
| 用途 | 科研检测 |
| 英文名称 | MS-275 |
| 包装规格 | 1MG |
| CAS编号 | 209783-80-2 |
| 别名 | MS-275 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C21H20N4O3
分子量:376.42
溶剂:DMSO (25 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):HDAC inhibitor
Function / Pharmacology:Potent HDAC inhibitor. Selective for HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM) and HDAC8 (IC50 > 100 μM).1 In vivo, MS-275 has been shown to inhibit tumor growth via induction of the tumor supressors p21WAF1/CIP1 and gelsolin2 and to block cell proliferation in a variety of cancer cell lines3,4. The compound has also shown significant anti-rheumatic activity in rat and mouse arthritis models.5
分子式:C21H20N4O3
分子量:376.42
溶剂:DMSO (25 mg/ml)
性状:Pale yellow solid
存储:-20°C
Activity (short version):HDAC inhibitor
Function / Pharmacology:Potent HDAC inhibitor. Selective for HDAC1 (IC50 = 300 nM) over HDAC3 (IC50 = 8 μM) and HDAC8 (IC50 > 100 μM).1 In vivo, MS-275 has been shown to inhibit tumor growth via induction of the tumor supressors p21WAF1/CIP1 and gelsolin2 and to block cell proliferation in a variety of cancer cell lines3,4. The compound has also shown significant anti-rheumatic activity in rat and mouse arthritis models.5
