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GW-2580
- 英文名称：GW-2580
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10553
- cas：870483-87-7
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-10-31
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10553 |
| 用途 | 科研检测 |
| 英文名称 | GW-2580 |
| 包装规格 | 1MG |
| CAS编号 | 870483-87-7 |
| 别名 | GW-2580 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C20H22N4O3
分子量:366.32
溶剂:DMSO (40 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):cFMS kinase inhibitor
Function / Pharmacology:Potent and selective inhibitor of cFMS receptor kinase. Completely inhibits cFMS in vitro at 60 nM with no activity against 26 other kinases1. Completely inhibits CSF-1 induced growth of mouse M-NFS-60 myeloid cells and human monocytes (at 1 μM)1. Completely inhibits bone degradation in human osteoclasts, rat calvaria and fetal long bone1. Inhibits LPS-induced TNF production in mice. Abrogates infiltration of macrophages into synovial joints of arthritic mice2. Active in vivo.
分子式:C20H22N4O3
分子量:366.32
溶剂:DMSO (40 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):cFMS kinase inhibitor
Function / Pharmacology:Potent and selective inhibitor of cFMS receptor kinase. Completely inhibits cFMS in vitro at 60 nM with no activity against 26 other kinases1. Completely inhibits CSF-1 induced growth of mouse M-NFS-60 myeloid cells and human monocytes (at 1 μM)1. Completely inhibits bone degradation in human osteoclasts, rat calvaria and fetal long bone1. Inhibits LPS-induced TNF production in mice. Abrogates infiltration of macrophages into synovial joints of arthritic mice2. Active in vivo.
