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Irinotecan HCl
- 英文名称:Irinotecan HCl
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10556
- cas:136572-09-3
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10556 |
用途 | 科研检测 |
英文名称 | Irinotecan HCl |
包装规格 | 1MG |
CAS编号 | 136572-09-3 |
别名 | Irinotecan HCl |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C33H38N4O6 ? HCl ? 3H20
分子量:586.69 ? 36.46 ? 54.05
溶剂:DMSO (50 mg/ml) Ethanol (4 mg/ml) Water (4 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Topoisomerase I inhibitor
Function / Pharmacology:Irinotecan is a semi-synthetic derivative of camptothecin that is an FDA approved anticancer drug. It is a prodrug that is converted by tissue esterases to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I.1,2 Although irinotecan is also a topoisomerase inhibitor, SN-38 is approximately 1000 times as potent in purified enzyme studies. In vitro cytotoxicity assays show much greater variability in potency between the two (2-2000 fold).3
分子式:C33H38N4O6 ? HCl ? 3H20
分子量:586.69 ? 36.46 ? 54.05
溶剂:DMSO (50 mg/ml) Ethanol (4 mg/ml) Water (4 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Topoisomerase I inhibitor
Function / Pharmacology:Irinotecan is a semi-synthetic derivative of camptothecin that is an FDA approved anticancer drug. It is a prodrug that is converted by tissue esterases to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I.1,2 Although irinotecan is also a topoisomerase inhibitor, SN-38 is approximately 1000 times as potent in purified enzyme studies. In vitro cytotoxicity assays show much greater variability in potency between the two (2-2000 fold).3