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SB 203580
- 英文名称:SB 203580
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10574
- cas:152121-47-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10574 |
用途 | 科研检测 |
英文名称 | SB 203580 |
包装规格 | 1MG |
CAS编号 | 152121-47-6 |
别名 | SB 203580 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C21H16N3OSF
分子量:377.44
溶剂:DMSO (100 mg/ml) Ethanol (10 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):p38 MAP kinase inhibitor
Function / Pharmacology:A potent and selective inhibitor of p38 MAP kinase, IC50=50 and 500 nM for p38 and p38β2 respectively. No other kinases (in a panel of 30) were significantly inhibited including p38γ and δ at 10 μM2. A potent inhibitor of inflammatory cytokine production (IC50=15-25 mg/kg in mice and rats) in animal models of arthritis, bone resorption, endotoxin shock and immune function3.
分子式:C21H16N3OSF
分子量:377.44
溶剂:DMSO (100 mg/ml) Ethanol (10 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):p38 MAP kinase inhibitor
Function / Pharmacology:A potent and selective inhibitor of p38 MAP kinase, IC50=50 and 500 nM for p38 and p38β2 respectively. No other kinases (in a panel of 30) were significantly inhibited including p38γ and δ at 10 μM2. A potent inhibitor of inflammatory cytokine production (IC50=15-25 mg/kg in mice and rats) in animal models of arthritis, bone resorption, endotoxin shock and immune function3.