|
Vismodegib
- 英文名称：Vismodegib
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10581
- cas：879085-55-9
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10581 |
| 用途 | 科研检测 |
| 英文名称 | Vismodegib |
| 包装规格 | 1MG |
| CAS编号 | 879085-55-9 |
| 别名 | Vismodegib |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:99% by TLC and HPLC;NMR (Conforms)
分子式:C19H14Cl2N2O3S
分子量:421.30
溶剂:DMSO (200 mg/ml), Ethanol (10 mg/ml)
性状:Off-white or beige solid
存储:-20°C
Activity (short version):Sonic Hedgehog signaling pathway inhibitor
Function / Pharmacology:A potent and selective Hedgehog (Hh) pathway signaling inhibitor antagonizing SMO with a Ki of 1.3 nM).1 Alters intracellular Ca2+ homeostasis and inhibits growth of cisplatin-resistant lung cancer cells.2 Inhibits two ABC transporters, ABCG2/BCRP and ABCB1/Pgp, IC50s=1.4 and 3.0 μM respectively.3 Clinically useful for the treatment of basal cell carcinoma.4 Inhibits proliferation and induces apoptosis in colon cancer cell lines.
分子式:C19H14Cl2N2O3S
分子量:421.30
溶剂:DMSO (200 mg/ml), Ethanol (10 mg/ml)
性状:Off-white or beige solid
存储:-20°C
Activity (short version):Sonic Hedgehog signaling pathway inhibitor
Function / Pharmacology:A potent and selective Hedgehog (Hh) pathway signaling inhibitor antagonizing SMO with a Ki of 1.3 nM).1 Alters intracellular Ca2+ homeostasis and inhibits growth of cisplatin-resistant lung cancer cells.2 Inhibits two ABC transporters, ABCG2/BCRP and ABCB1/Pgp, IC50s=1.4 and 3.0 μM respectively.3 Clinically useful for the treatment of basal cell carcinoma.4 Inhibits proliferation and induces apoptosis in colon cancer cell lines.
