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Vandetanib
- 英文名称:Vandetanib
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10583
- cas:443913-73-3
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10583 |
用途 | 科研检测 |
英文名称 | Vandetanib |
包装规格 | 1MG |
CAS编号 | 443913-73-3 |
别名 | Vandetanib |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C22H24BrFN4O2
分子量:475.35
溶剂:DMSO (30 mg/ml) Ethanol (10 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):VEGFRK inhibitor
Function / Pharmacology:A potent and selective inhibitor of VEGFR2, (KDR IC50 = 40 nM). Also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC50 = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC50 = 500 nM) but shows selectivity against a panel of other tyrosine and serine-threonine kinases. Inhibits colony formation in seven cancer cell lines2. Displays anti-angiogenesis activity3.
分子式:C22H24BrFN4O2
分子量:475.35
溶剂:DMSO (30 mg/ml) Ethanol (10 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):VEGFRK inhibitor
Function / Pharmacology:A potent and selective inhibitor of VEGFR2, (KDR IC50 = 40 nM). Also inhibits fms-like tyrosine kinase 4 (VEGFR3, IC50 = 110 nM) and epidermal growth factor receptor (EGFR/HER1, IC50 = 500 nM) but shows selectivity against a panel of other tyrosine and serine-threonine kinases. Inhibits colony formation in seven cancer cell lines2. Displays anti-angiogenesis activity3.