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Picropodophyllotoxin
- 英文名称:Picropodophyllotoxin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10587
- cas:477-47-4
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10587 |
用途 | 科研检测 |
英文名称 | Picropodophyllotoxin |
包装规格 | 1MG |
CAS编号 | 477-47-4 |
别名 | Picropodophyllotoxin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:97% by TLC,;NMR (Conforms)
分子式:C22 H22 O8
分子量:414.42
溶剂:DMSO (40 mg/ml)
性状:White solid
存储:RT
Activity (short version):IGF1R inhibitor
Function / Pharmacology:Potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP1. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC50 ~ 1 nM1. Displays antiproliferative activity in numerous tumor cell lines, IC50 = 0.05 - 15 ?M2. Exhibits antiangiogenic activitiy3. Attenuates intimal hyperplasia after vascular injury4. Active in vivo.
分子式:C22 H22 O8
分子量:414.42
溶剂:DMSO (40 mg/ml)
性状:White solid
存储:RT
Activity (short version):IGF1R inhibitor
Function / Pharmacology:Potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP1. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC50 ~ 1 nM1. Displays antiproliferative activity in numerous tumor cell lines, IC50 = 0.05 - 15 ?M2. Exhibits antiangiogenic activitiy3. Attenuates intimal hyperplasia after vascular injury4. Active in vivo.