纯度:99% by HPLC,;NMR (Conforms)
分子式:C14H9N4O5 Na
分子量:336.23
溶剂:DMSO (3 mg/ml) 1:1DMF/EtOH (20 mg/ml)
性状:Orange solid
存储:RT
Activity (short version):SR calcium release inhibitor
Function / Pharmacology:Inhibits release of Ca2+ from sarcoplasmic reticulum via inhibition of ryanodine receptor channels with selectivity for RYR1 and RYR3 over RYR2.1 Protects against quisqualate and NMDA-induced cytotoxicity in cultured cerebral cortical neurons.2 Displays neuroprotective effects.3 Prevents cell death in neural progenitor cells derived from Wolfram syndrome iPS cells.4