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Pirfenidone
- 英文名称:Pirfenidone
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10635
- cas:53179-13-8
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10635 |
用途 | 科研检测 |
英文名称 | Pirfenidone |
包装规格 | 1MG |
CAS编号 | 53179-13-8 |
别名 | Pirfenidone |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C12H11NO
分子量:185.23
溶剂:DMSO (20 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):Antifibrotic
Function / Pharmacology:Antifibrotic agent. Prevents lung fibrosis in bleomycin-induced animal models.1 Down-regulates bleomycin-induced overexpression of lung procollagen I and III genes.2 Up-regulates RGS2 (Regulator of G-protein Signaling 2) which represents a new mechanism of pirfenidone action.3 Inhibits fibroblast proliferation.4 Suppresses TNFα production at the translational level.5 Scavenges hydroxyl radicals and inhibits lipid peroxidation in a dose-dependent manner.6 Recently approved therapeutic agent for idiopathic pulmonary fibrosis.7 Orally active.
分子式:C12H11NO
分子量:185.23
溶剂:DMSO (20 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):Antifibrotic
Function / Pharmacology:Antifibrotic agent. Prevents lung fibrosis in bleomycin-induced animal models.1 Down-regulates bleomycin-induced overexpression of lung procollagen I and III genes.2 Up-regulates RGS2 (Regulator of G-protein Signaling 2) which represents a new mechanism of pirfenidone action.3 Inhibits fibroblast proliferation.4 Suppresses TNFα production at the translational level.5 Scavenges hydroxyl radicals and inhibits lipid peroxidation in a dose-dependent manner.6 Recently approved therapeutic agent for idiopathic pulmonary fibrosis.7 Orally active.