纯度:98% by TLC,;NMR (Conforms)
分子式:C21H25NO ?CH4SO3
分子量:403.53
溶剂:DMSO (35 mg/ml) Ethanol (5 mg/ml)
性状:White solid
存储:RT
Activity (short version):Induces remyelination of neurons
Function / Pharmacology:Centrally acting M1 muscarinic acetylcholine receptor antagonist (Ki=0.59 nM, rat).1 Also inhibits the dopamine transporter (Ki=160 nM).2 Enhances remyelination and significantly decreases clinical severity in the experimental autoimmune encephalomyelitis model of relapsing-remitting multiple sclerosis alone or in combination with immunosuppressive agents.3 Inhibits hepatitis C virus infection.4