纯度:98% by HPLC,;NMR (Conforms)
分子式:C24H36N4O6S2
分子量:540.71
溶剂:DMSO (10 mg/ml)
性状:Colorless waxy solid - vials may appear empty to visual inspection
存储:-20°C
Activity (short version):HDAC inhibitor
Function / Pharmacology:A potent and selective inhibitor of class I histone deacetylases (HDACs), IC50 = 36, 47, 510 and 14,000 nM for HDAC1, 2, 4 and HDAC6, respectively1. Induces apoptosis in a variety of cell lines2 and displays antitumor activity in mouse models3. Recently approved for clinical use in T-cell lymphoma4.