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Piperlongumine
  • 英文名称:Piperlongumine
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B10654
  • cas:20069-09-4
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-12
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B10654
用途 科研检测
英文名称 Piperlongumine
包装规格 1MG
CAS编号 20069-09-4
别名 Piperlongumine
纯度 98+%
分子式
是否进口
纯度:98% by TLC,;NMR (Conforms)
分子式:C17H19NO5
分子量:317.34
溶剂:DMSO (25 mg/ml)
性状:Cream-colored solid
存储:RT
Activity (short version):Glutathione sponge / Increases ROS levels
Function / Pharmacology:Elevates cellular levels of reactive oxygen species selectively in cancer cell lines1. Irreversible glutathionylation leading to depletion of cellular glutathione is associated with its cellular toxicity2. Piperlongamine does not appear to have any effect on normal cells. Displays anti-tumor effects in a mouse xenograft tumor model as well as in spontaneously formed malignant breast tumors in mice1. Elevation of ROS levels may be due to inhibition of ubiquitin-proteasome system at a pre-proteasomal step.3
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