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Nocodazole
- 英文名称:Nocodazole
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10658
- cas:31430-18-9
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10658 |
用途 | 科研检测 |
英文名称 | Nocodazole |
包装规格 | 1MG |
CAS编号 | 31430-18-9 |
别名 | Nocodazole |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C14H11N3O3S
分子量:301.32
溶剂:DMSO (10 mg/ml)
性状:White or off-white solid
存储:RT
Activity (short version):Microtubule inhibitor
Function / Pharmacology:Nocodazole is an antimitotic agent that disrupts microtubules by binding to β tubulin and thereby inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex.1,2 Arrests cell cycle at G2/M phase. Stimulates the intrinsic GTPase activity of tubulin.3 Nocodazole activates the JNK/SAPK signaling pathway and induces apoptosis in a variety of cell lines.4 Increases Cas9-mediated editing frequencies5 and increased CRISPR-mediated HDR DNA repair6. Cell permeable.
分子式:C14H11N3O3S
分子量:301.32
溶剂:DMSO (10 mg/ml)
性状:White or off-white solid
存储:RT
Activity (short version):Microtubule inhibitor
Function / Pharmacology:Nocodazole is an antimitotic agent that disrupts microtubules by binding to β tubulin and thereby inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex.1,2 Arrests cell cycle at G2/M phase. Stimulates the intrinsic GTPase activity of tubulin.3 Nocodazole activates the JNK/SAPK signaling pathway and induces apoptosis in a variety of cell lines.4 Increases Cas9-mediated editing frequencies5 and increased CRISPR-mediated HDR DNA repair6. Cell permeable.