纯度:>98% by HPLC;NMR (Conforms)
分子式:C15H18N2O
分子量:242.32
溶剂:DMSO (20 mg/ml)
性状:White to off-white solid
存储:-20°C
Activity (short version):Acetylcholinesterase inhibitor
Function / Pharmacology:Huperzine A (102518-79-6) is a nootropic alkaloid from the club moss Huperzia serrata that reversibly inhibits acetylcholinesterase (AChE, preferentially the tetrameric form, Ki = 7 nM)1, and antagonizes NMDA receptors (IC50 rat cerebral cortex = 126 μM)2. It is thought to have cognitive-enhancing properties, including amelioration of Alzheimer’s disease.3,4 Recently, it has also been shown to rescue ovarian function in rats5 as well as display analgesic activity in a rat spinal cord compression model6.