纯度:98% by HPLC;NMR (Conforms)
分子式:C10H13N5O3
分子量:251.24
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):AMPK activator
Function / Pharmacology:An adenosine analog lacking the hydroxyl at the 3’ position. Inhibits PARP1 and polyadenylation2. Displays anti-inflammatory effects1,3 and neuroprotective effects by inhibiting A?-induced apoptosis in hippocampal neurons4. Induces apoptosis in a variety of cancer cell lines5. Displays antiobesity effects.6 Inhibits cell senescence via activation of AMPK.7 Maintains stem cell pluripotency and increases iPS cell generation efficiency.8