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Veliparib 2HCl
- 英文名称:Veliparib 2HCl
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10675
- cas:912445-05-7
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10675 |
用途 | 科研检测 |
英文名称 | Veliparib 2HCl |
包装规格 | 1MG |
CAS编号 | 912445-05-7 |
别名 | Veliparib 2HCl |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C13H16N4O·2HCl
分子量:317.22
溶剂:DMSO (30 mg/ml) Water (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):PARP 1&2 inhibitor
Function / Pharmacology:Potent and selective PARP-inhibitor with Ki values of 5.2 nM and 2.9 nM for PARP-1 and PARP-2, respectively.1 Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometrial carcinoma cells3. Also improves sensitivity to DNA replication inhibitor cisplatin in human oral carcinoma cells.4
分子式:C13H16N4O·2HCl
分子量:317.22
溶剂:DMSO (30 mg/ml) Water (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):PARP 1&2 inhibitor
Function / Pharmacology:Potent and selective PARP-inhibitor with Ki values of 5.2 nM and 2.9 nM for PARP-1 and PARP-2, respectively.1 Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometrial carcinoma cells3. Also improves sensitivity to DNA replication inhibitor cisplatin in human oral carcinoma cells.4