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Veliparib 2HCl
- 英文名称：Veliparib 2HCl
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10675
- cas：912445-05-7
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10675 |
| 用途 | 科研检测 |
| 英文名称 | Veliparib 2HCl |
| 包装规格 | 1MG |
| CAS编号 | 912445-05-7 |
| 别名 | Veliparib 2HCl |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C13H16N4O·2HCl
分子量:317.22
溶剂:DMSO (30 mg/ml) Water (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):PARP 1&2 inhibitor
Function / Pharmacology:Potent and selective PARP-inhibitor with Ki values of 5.2 nM and 2.9 nM for PARP-1 and PARP-2, respectively.1 Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometrial carcinoma cells3. Also improves sensitivity to DNA replication inhibitor cisplatin in human oral carcinoma cells.4
分子式:C13H16N4O·2HCl
分子量:317.22
溶剂:DMSO (30 mg/ml) Water (40 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):PARP 1&2 inhibitor
Function / Pharmacology:Potent and selective PARP-inhibitor with Ki values of 5.2 nM and 2.9 nM for PARP-1 and PARP-2, respectively.1 Restores sensitivity to DNA alkylator/methylator temozolomide in glioma cells and xenografts2, and enhances radiotherapy sensitivity in endometrial carcinoma cells3. Also improves sensitivity to DNA replication inhibitor cisplatin in human oral carcinoma cells.4
