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Echinomycin
- 英文名称：Echinomycin
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10676
- cas：512-64-1
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10676 |
| 用途 | 科研检测 |
| 英文名称 | Echinomycin |
| 包装规格 | 1MG |
| CAS编号 | 512-64-1 |
| 别名 | Echinomycin |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:>97% by HPLC;NMR (Conforms)
分子式:C51H64N12O12S2
分子量:1101.26
溶剂:DMSO (5 mg/ml)
性状:White to beige solid
存储:-20°C
Activity (short version):HIF1α inhibitor
Function / Pharmacology:Echinomycin is a potent and selective hypoxia inducible factor 1α (HIF-1α) inhibitor. It binds to DNA via bifunctional intercalation, blocking the interaction of HIF-1α.1 Protects mice against relapsed acute myeloid leukemia with no effect on hematopoietic stem cells.2 Selectively eliminates cancer stem cells in mouse lymphoma and human AML xenogeneic models.3 A very useful tool for probing genes regulated by HIF1α.4
分子式:C51H64N12O12S2
分子量:1101.26
溶剂:DMSO (5 mg/ml)
性状:White to beige solid
存储:-20°C
Activity (short version):HIF1α inhibitor
Function / Pharmacology:Echinomycin is a potent and selective hypoxia inducible factor 1α (HIF-1α) inhibitor. It binds to DNA via bifunctional intercalation, blocking the interaction of HIF-1α.1 Protects mice against relapsed acute myeloid leukemia with no effect on hematopoietic stem cells.2 Selectively eliminates cancer stem cells in mouse lymphoma and human AML xenogeneic models.3 A very useful tool for probing genes regulated by HIF1α.4
