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SN-38
- 英文名称：SN-38
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10677
- cas：86639-52-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10677 |
| 用途 | 科研检测 |
| 英文名称 | SN-38 |
| 包装规格 | 1MG |
| CAS编号 | 86639-52-3 |
| 别名 | SN-38 |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C22H20N2O5
分子量:392.41
溶剂:DMSO (40 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):DNA topoisomerase I inhibitor
Function / Pharmacology:Active metabolite of CPT-11 that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 μM in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 μM respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).
分子式:C22H20N2O5
分子量:392.41
溶剂:DMSO (40 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):DNA topoisomerase I inhibitor
Function / Pharmacology:Active metabolite of CPT-11 that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 μM in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 μM respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).
