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Topotecan HCl
- 英文名称:Topotecan HCl
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10702
- cas:119413-54-6
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10702 |
用途 | 科研检测 |
英文名称 | Topotecan HCl |
包装规格 | 1MG |
CAS编号 | 119413-54-6 |
别名 | Topotecan HCl |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by HPLC;NMR (Conforms)
分子式:C23H23N3O5 ? HCl
分子量:457.91
溶剂:DMSO (50 mg/ml); water (50 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):DNA topoisomerase I inhibitor
Function / Pharmacology:Topotecan HCl is a water-soluble and orally active analog of camptothecin, a DNA topoisomerase I inhibitor.1 Inhibits topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells, IC50s = 13 and 2 nM respectively.2 Downregulates B-Myb and MycN expression in neuroblastoma cells.3 A clinically useful anticancer agent.
分子式:C23H23N3O5 ? HCl
分子量:457.91
溶剂:DMSO (50 mg/ml); water (50 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):DNA topoisomerase I inhibitor
Function / Pharmacology:Topotecan HCl is a water-soluble and orally active analog of camptothecin, a DNA topoisomerase I inhibitor.1 Inhibits topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells, IC50s = 13 and 2 nM respectively.2 Downregulates B-Myb and MycN expression in neuroblastoma cells.3 A clinically useful anticancer agent.