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CUDC-101
- 英文名称:CUDC-101
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10708
- cas:1012054-59-9
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10708 |
用途 | 科研检测 |
英文名称 | CUDC-101 |
包装规格 | 1MG |
CAS编号 | 1012054-59-9 |
别名 | CUDC-101 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:99% by HPLC;NMR (Conforms)
分子式:C24H26N4O4
分子量:434.49
溶剂:DMSO (25 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Dual HDAC and EGFR inhibitor
Function / Pharmacology:A novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2, IC50 = 4.4, 2.4 and 15.7 nM respectively.1 It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.1,2
分子式:C24H26N4O4
分子量:434.49
溶剂:DMSO (25 mg/ml)
性状:White or off-white solid
存储:-20°C
Activity (short version):Dual HDAC and EGFR inhibitor
Function / Pharmacology:A novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2, IC50 = 4.4, 2.4 and 15.7 nM respectively.1 It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.1,2