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Stattic
- 英文名称:Stattic
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10714
- cas:19983-44-9
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10714 |
用途 | 科研检测 |
英文名称 | Stattic |
包装规格 | 1MG |
CAS编号 | 19983-44-9 |
别名 | Stattic |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C8H5NO4S
分子量:211.20
溶剂:DMSO (10 mg/ml) Ethanol (1 mg/ml)
性状:Light yellow solid
存储:-20°C
Activity (short version):STAT3 inhibitor
Function / Pharmacology:STAT3 inhibitor. Inhibits binding of tyrosine-phosphorylated peptides to STAT3 SH2 domain and inhibiting STAT3 activation, dimerization and nuclear translocation1. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. Alkyates four cysteine residues on STAT32. Exhibits potent antitumor activity3. Protects against angiotensin II-induced vascular dysfunction and hypertension4. An extremely useful tool to probe involvement of STAT3 in cellular signaling.
分子式:C8H5NO4S
分子量:211.20
溶剂:DMSO (10 mg/ml) Ethanol (1 mg/ml)
性状:Light yellow solid
存储:-20°C
Activity (short version):STAT3 inhibitor
Function / Pharmacology:STAT3 inhibitor. Inhibits binding of tyrosine-phosphorylated peptides to STAT3 SH2 domain and inhibiting STAT3 activation, dimerization and nuclear translocation1. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. Alkyates four cysteine residues on STAT32. Exhibits potent antitumor activity3. Protects against angiotensin II-induced vascular dysfunction and hypertension4. An extremely useful tool to probe involvement of STAT3 in cellular signaling.