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FAK inhibitor 14
- 英文名称:FAK inhibitor 14
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10721
- cas:4506-66-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10721 |
用途 | 科研检测 |
英文名称 | FAK inhibitor 14 |
包装规格 | 1MG |
CAS编号 | 4506-66-5 |
别名 | FAK inhibitor 14 |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C6H10N4 · 4HCl
分子量:284.02
溶剂:DMSO (20 mg/ml) water (15 mg/ml)
性状:Grey solid
存储:-20°C
Activity (short version):FAK inhibitor
Function / Pharmacology:Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo. Induces regression of pancreatic tumors2 and glioblastoma3. Displays antiangiogenic activity4.
分子式:C6H10N4 · 4HCl
分子量:284.02
溶剂:DMSO (20 mg/ml) water (15 mg/ml)
性状:Grey solid
存储:-20°C
Activity (short version):FAK inhibitor
Function / Pharmacology:Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo. Induces regression of pancreatic tumors2 and glioblastoma3. Displays antiangiogenic activity4.