纯度:98% by HPLC;NMR (Conforms)
分子式:C24H25FNO4 Na
分子量:466.45
溶剂:DMSO (40 mg/ml) Water (10 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):HMG CoA reductase inhibitor
Function / Pharmacology:Potent inhibitor of HMG-CoA reductase, IC50=40-100 nM.1 Clinically useful, orally active antihypercholesterolemic agent. Inhibits vascular smooth muscle proliferation, IC50=70 nM.2 Displays antineuroinflammatory activity.3 Prevents lung adenocarcinoma bone metastasis by triggering autophagy.4 Attenuates cell proliferation in hepatocellular carcinoma.5