纯度:97% by HPLC;NMR (Conforms)
分子式:C19H30O4
分子量:322.44
溶剂:DMSO (10 mg/ml)
性状:Yellow/Orange Oil
存储:-20°C
Activity (short version):MPTP inhibitor
Function / Pharmacology:Inhibits the Ca2+ dependent mitochondrial permeability transition pore (MPTP) without inhibiting respiration.1 Maximum effect on Ca2+ retention capacity of rat liver mitochondria at 100 μM. Inhibits etoposide-induced apoptosis in in L929 cells at 5 μM via inhibition of cytochrome c release.2 Delays rotenone-induced cardiac dysfunction in a zebrafish model of development and cardiovascular function.3 Substrate for various quinone oxidoreductases.4,5