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BADGE
- 英文名称:BADGE
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10745
- cas:1675-54-3
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-12
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10745 |
用途 | 科研检测 |
英文名称 | BADGE |
包装规格 | 1MG |
CAS编号 | 1675-54-3 |
别名 | BADGE |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:95% by HPLC;NMR (Conforms)
分子式:C21H24O4
分子量:340.41
溶剂:DMSO (30 mg/ml) Ethanol (15 mg/ml)
性状:Colorless low melting point solid or viscous oil depending upon temperature
存储:-20°C
Activity (short version):PPARγ antagonist
Function / Pharmacology:PPARγ antagonist with μM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARδ and PPARα. Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPARγ and abolishes its anti-inflammatory effects in a mouse model1. Induces apoptosis via PPARγ-independent mechanisms2. Induces adipogenesis in human and mouse mesenchymal stromal stem cells and in mouse 3T3-L1 preadipocytes at low nM concentrations via a PPARγ independent mechanism3. Increases osteoblastogenesis and bone mass in a mouse model4. Active in vivo.
分子式:C21H24O4
分子量:340.41
溶剂:DMSO (30 mg/ml) Ethanol (15 mg/ml)
性状:Colorless low melting point solid or viscous oil depending upon temperature
存储:-20°C
Activity (short version):PPARγ antagonist
Function / Pharmacology:PPARγ antagonist with μM affinity in 3T3-L1 and 3T3-F442A preadipocyte cells. Selective over PPARδ and PPARα. Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPARγ and abolishes its anti-inflammatory effects in a mouse model1. Induces apoptosis via PPARγ-independent mechanisms2. Induces adipogenesis in human and mouse mesenchymal stromal stem cells and in mouse 3T3-L1 preadipocytes at low nM concentrations via a PPARγ independent mechanism3. Increases osteoblastogenesis and bone mass in a mouse model4. Active in vivo.