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Monastrol
- 英文名称：Monastrol
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10752
- cas：254753-54-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10752 |
| 用途 | 科研检测 |
| 英文名称 | Monastrol |
| 包装规格 | 1MG |
| CAS编号 | 254753-54-3 |
| 别名 | Monastrol |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC;NMR (Conforms)
分子式:C14H16N2O3S
分子量:292.35
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Kinesin Eg5 and mitosis inhibitor
Function / Pharmacology:Potent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 μM).2 Mimics the effect of amyloid β on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4
分子式:C14H16N2O3S
分子量:292.35
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:Beige solid
存储:-20°C
Activity (short version):Kinesin Eg5 and mitosis inhibitor
Function / Pharmacology:Potent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 μM).2 Mimics the effect of amyloid β on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4
