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Roflumilast
- 英文名称：Roflumilast
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10758
- cas：162401-32-3
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-23
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10758 |
| 用途 | 科研检测 |
| 英文名称 | Roflumilast |
| 包装规格 | 1MG |
| CAS编号 | 162401-32-3 |
| 别名 | Roflumilast |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by HPLC,;NMR (Conforms)
分子式:C17H14N2Cl2F2O3
分子量:403.21
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):PDE4 inhibitor
Function / Pharmacology:Potent and selective phosphodiesterase (PDE4) inhibitor, IC50=0.7, 0.9, 0.7, 0.2 nM for PDE4A1, PDE4A4, PDE4B1 and PDE4B2 respectively1. Clinically useful agent for treatment of COPD2. Improves sensory gating in humans3 and improves memory in rodent models4. Mimics calorie restriction effects via activation of AMPK/SIRT1 and protects against diabetic nephropathy5. Reduces weight gain by increasing energy expenditure and improves glucose metabolism in mice6.
分子式:C17H14N2Cl2F2O3
分子量:403.21
溶剂:DMSO (25 mg/ml)
性状:White solid
存储:-20°C
Activity (short version):PDE4 inhibitor
Function / Pharmacology:Potent and selective phosphodiesterase (PDE4) inhibitor, IC50=0.7, 0.9, 0.7, 0.2 nM for PDE4A1, PDE4A4, PDE4B1 and PDE4B2 respectively1. Clinically useful agent for treatment of COPD2. Improves sensory gating in humans3 and improves memory in rodent models4. Mimics calorie restriction effects via activation of AMPK/SIRT1 and protects against diabetic nephropathy5. Reduces weight gain by increasing energy expenditure and improves glucose metabolism in mice6.
