纯度:98% by TLC;NMR (Conforms)
分子式:C16H16F3NO HCl
分子量:331.76
溶剂:DMSO (>25 mg/ml)
性状:Beige waxy solid
存储:-20°C
Activity (short version):Fluoxetine metabolite
Function / Pharmacology:Metabolite of fluoxetine.3 Induces long QT syndrome via slow delayed rectifier potassium current block.1 Time dependent inhibitor of CYP2C19 and CYP3A4.2 The S-isomer of desmethylfluoxetine is the active N-demethylated metabolite responsible for the persistently potent and selective inhibition of serotonin uptake in vivo.3 Potent inhibitor of coxsackievirus replication acting via inhibition of viral RNA synthesis.4 State-dependent TREK-2 blocker.5