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Probucol
  • 英文名称:Probucol
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B10769
  • cas:23288-49-5
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-12
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B10769
用途 科研检测
英文名称 Probucol
包装规格 1MG
CAS编号 23288-49-5
别名 Probucol
纯度 98+%
分子式
是否进口
纯度:98% by HPLC / TLC;NMR (Conforms)
分子式:C31H48O2S2
分子量:516.84
溶剂:DMSO (100 mg/ml) Ethanol (50 mg/ml)
性状:Off-white solid
存储:RT
Activity (short version):Antioxidant hypercholesterolemic agent
Function / Pharmacology:Probucol (23288-49-5) is a unique antilipidemic drug which inhibits the oxidation of LDL cholesterol preventing the genesis of macrophage-derived foam cells and thus suppressing the formation of atherosclerotic vascular lesions.1 It inhibits ABCA1-mediated cholesterol efflux without influencing scavenger receptor (class B type 1)-mediated efflux.2 It enhances mitophagy and improves survival, locomotor function and dopaminergic neuron loss in zebrafish and fly models of mitochondrial damage.3 It attenuates NF-kB/NLRP3 signaling and augments Nrf-2-mediated antioxidant defense in nerve injury models.4 Improves learning and memory in aging mice.5 It protects neuronal cells against peroxide-induced damage and directly activates glutathione peroxidase-1.6
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