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8-pCPT-2-O-Me-cAMP-AM
  • 英文名称:8-pCPT-2-O-Me-cAMP-AM
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B10792
  • cas:1152197-23-3
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-16
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B10792
用途 科研检测
英文名称 8-pCPT-2-O-Me-cAMP-AM
包装规格 1MG
CAS编号 1152197-23-3
别名 8-pCPT-2-O-Me-cAMP-AM
纯度 98+%
分子式
是否进口
纯度:97% by HPLC
分子式:C20H21ClN5O8PS
分子量:557.91
溶剂:DMSO (50 mg/ml)
性状:solid
存储:-20°C
Activity (short version):Epac activator
Function / Pharmacology:A potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator1. Induces RAP1 activation and insulin secretion in pancreatic beta cell lines2-5. Induces vascular relaxation in rat mesenteric artery6. The acetoxymethyl ester confers increased cell-permeability and is cleaved by endogenous esterases to yield the active compound, 8-pCPT-2'-O-Me-cAMP. Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the acetoxymethyl ester and reduce cell permeability.
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