纯度:>98% by TLC,;NMR (Conforms)
分子式:C16H30O
分子量:238.42
溶剂:DMSO (35 mg / ml) Ethanol (35 mg/ml)
性状:Colorless oil
存储:-20°C
Activity (short version):Cardioprotective and neuroprotective agent
Function / Pharmacology:Muscone (541-91-3) is a macrocyclic ketone found naturally in a glandular secretion of the musk deer which acts at human odorant receptor OR5AN1 and is used in perfumes.1 It suppresses inflammatory responses and neuronal damage in various models including a rat model of cervical spondylotic myelopathy2 and relieves inflammatory pain acting via the NOX4/JAK2-STAT3 and NLRP3 inflammasome pathway3. In the cardiovascular system it alleviates myocardial ischemia-reperfusion injury4 and improves cardiac function in mice after myocardial infarction5 via enhancement of angiogenesis6.