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Pomalidomide
- 英文名称：Pomalidomide
- 品牌：WYTSCI
- 产地：进口
- 型号：1MG
- 货号：WT-AY-B10804
- cas：19171-19-8
- 价格： ￥1/mg
- 发布日期： 2025-04-10
- 更新日期： 2025-05-12
产品详请
| 产地 | 进口 |
| 品牌 | WYTSCI |
| 货号 | WT-AY-B10804 |
| 用途 | 科研检测 |
| 英文名称 | Pomalidomide |
| 包装规格 | 1MG |
| CAS编号 | 19171-19-8 |
| 别名 | Pomalidomide |
| 纯度 | 98+% |
| 分子式 | |
| 是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C13H11N3O4
分子量:273.24
溶剂:DMSO (50 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Cereblon ubiquitination inhibitor
Function / Pharmacology:Thalidomide analog. Inhibits cereblon (CRBN) an E3 ubiquitin ligase, IC50 ~3 ?M for CRBN-DDB1 complex.1 Displays antiangiogenic and immunomodulatory activity in vivo potently inhibiting the production of TNF? and IL-2.2 Promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome.3 Conjugation with other ligands is a strategy to target proteins for in vivo proteasomal degradation via PROTACS.4,5
分子式:C13H11N3O4
分子量:273.24
溶剂:DMSO (50 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Cereblon ubiquitination inhibitor
Function / Pharmacology:Thalidomide analog. Inhibits cereblon (CRBN) an E3 ubiquitin ligase, IC50 ~3 ?M for CRBN-DDB1 complex.1 Displays antiangiogenic and immunomodulatory activity in vivo potently inhibiting the production of TNF? and IL-2.2 Promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome.3 Conjugation with other ligands is a strategy to target proteins for in vivo proteasomal degradation via PROTACS.4,5
