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Riluzole
- 英文名称:Riluzole
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10815
- cas:1744-22-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-23
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10815 |
用途 | 科研检测 |
英文名称 | Riluzole |
包装规格 | 1MG |
CAS编号 | 1744-22-5 |
别名 | Riluzole |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:98% by TLC,;NMR (Conforms)
分子式:C8H5F3N2OS
分子量:234.20
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:RT
Activity (short version):Sodium channel blocker / Neuroprotective
Function / Pharmacology:Riluzole is a clinically useful drug for the treatment of amyotrophic lateral sclerosis (ALS).1 Riluzole inhibits glutamate release via inactivation of voltage-dependent ion channels, effects expression and signal transduction of glutamate receptors, and facilitates glutamate uptake.2,3,4 It has also been investigated as a treatment for depression and anxiety.5 Riluzole induced apoptosis in mGluR1-expressing melanoma cells6, inhibited cell proliferation in a U87MG glioblastoma model via blockage of glutamate release7, and inhibited the growth of brain tumor stem-like cells via downregulation of GLUT3.
分子式:C8H5F3N2OS
分子量:234.20
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:RT
Activity (short version):Sodium channel blocker / Neuroprotective
Function / Pharmacology:Riluzole is a clinically useful drug for the treatment of amyotrophic lateral sclerosis (ALS).1 Riluzole inhibits glutamate release via inactivation of voltage-dependent ion channels, effects expression and signal transduction of glutamate receptors, and facilitates glutamate uptake.2,3,4 It has also been investigated as a treatment for depression and anxiety.5 Riluzole induced apoptosis in mGluR1-expressing melanoma cells6, inhibited cell proliferation in a U87MG glioblastoma model via blockage of glutamate release7, and inhibited the growth of brain tumor stem-like cells via downregulation of GLUT3.