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Riluzole
  • 英文名称:Riluzole
  • 品牌:WYTSCI
  • 产地:进口
  • 型号:1MG
  • 货号:WT-AY-B10815
  • cas:1744-22-5
  • 价格: ¥1/mg
  • 发布日期: 2025-04-10
  • 更新日期: 2025-05-12
产品详请
产地 进口
品牌 WYTSCI
货号 WT-AY-B10815
用途 科研检测
英文名称 Riluzole
包装规格 1MG
CAS编号 1744-22-5
别名 Riluzole
纯度 98+%
分子式
是否进口
纯度:98% by TLC,;NMR (Conforms)
分子式:C8H5F3N2OS
分子量:234.20
溶剂:DMSO (25 mg/ml) Ethanol (25 mg/ml)
性状:White solid
存储:RT
Activity (short version):Sodium channel blocker / Neuroprotective
Function / Pharmacology:Riluzole is a clinically useful drug for the treatment of amyotrophic lateral sclerosis (ALS).1 Riluzole inhibits glutamate release via inactivation of voltage-dependent ion channels, effects expression and signal transduction of glutamate receptors, and facilitates glutamate uptake.2,3,4 It has also been investigated as a treatment for depression and anxiety.5 Riluzole induced apoptosis in mGluR1-expressing melanoma cells6, inhibited cell proliferation in a U87MG glioblastoma model via blockage of glutamate release7, and inhibited the growth of brain tumor stem-like cells via downregulation of GLUT3.
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