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Blebbistatin
- 英文名称:Blebbistatin
- 品牌:WYTSCI
- 产地:进口
- 型号:1MG
- 货号:WT-AY-B10823
- cas:674289-55-5
- 价格: ¥1/mg
- 发布日期: 2025-04-10
- 更新日期: 2025-05-16
产品详请
产地 | 进口 |
品牌 | WYTSCI |
货号 | WT-AY-B10823 |
用途 | 科研检测 |
英文名称 | Blebbistatin |
包装规格 | 1MG |
CAS编号 | 674289-55-5 |
别名 | Blebbistatin |
纯度 | 98+% |
分子式 | |
是否进口 | 是 |
纯度:>98% by TLC;NMR (Conforms)
分子式:C18H16N2O2
分子量:292.34
溶剂:DMSO (45 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Non-muscle myosin II inhibitor
Function / Pharmacology:Blebbistatin is a potent, selective, reversible, cell-permeable inhibitor of non-muscle myosin II (IC50 ~4 mM).1,2 During cell division it inhibits contraction of the cleavage furrow without disrupting mitosis.1 Blocks cell blebbing (hence its name) and rapidly disrupts directed cell migration and cytokinesis in many cell types.1 It promotes neurite outgrowth3 and is neuroprotective against vincristine-induced neurotoxicity in iPSC-derived neurons4.
分子式:C18H16N2O2
分子量:292.34
溶剂:DMSO (45 mg/ml)
性状:Yellow solid
存储:-20°C
Activity (short version):Non-muscle myosin II inhibitor
Function / Pharmacology:Blebbistatin is a potent, selective, reversible, cell-permeable inhibitor of non-muscle myosin II (IC50 ~4 mM).1,2 During cell division it inhibits contraction of the cleavage furrow without disrupting mitosis.1 Blocks cell blebbing (hence its name) and rapidly disrupts directed cell migration and cytokinesis in many cell types.1 It promotes neurite outgrowth3 and is neuroprotective against vincristine-induced neurotoxicity in iPSC-derived neurons4.